Report of a new case]. Yang DG. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. J Nutr 2001;131:1471-8. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. View abstract. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. View abstract. View abstract. Madisch A, Melderis H, Mayr G, et al. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Hinoshita F, Ogura Y, Suzuki Y, et al. J Neuroophthalmol. To learn more about how herbs are used to treat infertility, see this article. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. View abstract. Sheehan M, Rustin MHA, Atherton DJ, et al. Neth J Med 2005;63:119-20. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. . J Ethnopharmacol. Iran J Pharm Res 2012;11(2):541-8. Select a condition to view a list of vitamins. View abstract. Patel P, Aknouk M, Dawson A, et al. Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. View abstract. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Taking licorice might reduce the effects of blood pressure medications. Mattarello MJ, Karbowiak I, Ermolao A, and et al. View abstract. A., Braun, T. M., and Jacobson, J. J. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. Chin Med J (Engl.) (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) Preterm birth and licorice consumption during pregnancy. View abstract. *. 6. Int Immunopharmacol. Some of these health benefits have also . View abstract. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. BJU Int 2000;85:481-5. Burgess, J. Robles BJ, Sandoval AR, Dardon JD, Blas CA. View abstract. Chatterjee, N., Domoto-Reilly, K., Fecci, P. E., Schwamm, L. H., and Singhal, A. View abstract. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Lipids Health Dis 2011;10:29. View abstract. Akbari N, Asadimehr N, Kiani Z. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Scand.J Gastroenterol. View abstract. Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. Postgrad Med J 2003;79:115-6.. View abstract. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. View abstract. Hattori, T., Ikematsu, S., Koito, A., Matsushita, S., Maeda, Y., Hada, M., Fujimaki, M., and Takatsuki, K. Preliminary evidence for inhibitory effect of glycyrrhizin on HIV replication in patients with AIDS. It may disrupt the production of sex hormones ( 9 ). It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. Clin Rheumatol. View abstract. van Uum SH. View abstract. Ultrastruct Pathol 1992;16(5):529-535. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. View abstract. A laboratory evaluation of the antibacterial and cytotoxic effect of Liquorice when used as root canal medicament. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. Blood Press 2009;18:192-5. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. Microbiol Immunol 2000;44(9):799-804. Zhong.Xi.Yi.Jie.He.Za Zhi. Menopause 2002;9:145-50. But I didn't take it long enough to see any change. J Assoc Physicians India 1978;26(9):811-814. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. The U.S. Food and Drug . View abstract. View abstract. Chen LC, Chou MH, Lin MF, Yang LL. View abstract. Low doses of liquorice can induce hypertension encephalopathy. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. Complement Ther Clin Pract. View abstract. Previous studies have estimated that a dose of 1 to 5 grams (g) of licorice root daily is safe for most adults. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . This information may not fit your specific health circumstances. Lee YS, Lorenzo BJ, Koufis T, et al. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. View abstract. 2010;16(4):216-218. View abstract. 1991;11(4):199-202, 195. Br Med J 9-17-1977;2(6089):738-739. 2004;24(12):1084-1086. Wu G, Wu N, Li T, et al. 17. How Much Is Too Much? Visavadiya, N. P. and Narasimhacharya, A. V. Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. View abstract. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. Health Care Women Int. Chemical studies of Chinese licorice-roots. Schleimer, R. P. Potential regulation of inflammation in the lung by local metabolism of hydrocortisone. May Harm Baby During Pregnancy. Cureus 2021;13(7):e16454. 2 in the perioperative stage of laparoscopic cholecystectomy]. But, she survived . View abstract. Hyodo T, Taira T, Kumakura M, et al. Diane Calello, executive medical director of the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, discusses safe . Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. View abstract. Some medications are changed and broken down by the liver. Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M., and Kumada, H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Licorice might decrease how quickly the body breaks down methotrexate. View abstract. Wen Y, Tang Y, Li M, Lai Y. Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. That's because licorice real black licorice, not the phony licorice-flavored stuff flavored with anise oil . View abstract. N Engl J Med 1968;278(25):1381-1383. View abstract. Information from this source is evidence-based and objective, and without commercial influence. Electronic Code of Federal Regulations. View abstract. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Effect of licorice on reduction of body fat mass in healthy subjects. View abstract. Effect of shakuyaku-kanzoh-toh, a prescription composed of shakuyaku (Paeoniae Radix) and kanzoh (Glycyrrhizae Radix) on guinea pig ileum. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. Title 21. 2005 - 2023 WebMD LLC. Meng Xiangrui is an academic researcher. 2019;18(Suppl1):291-301. Dai DW, Singh I, Hershman JM. Nutr Res 2012;32(2):85-92. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Melzer J, Rosch W, Reichling J, et al. Licorice seems to change hormone levels in the body. Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. Immunology 1997;90(1):115-120. Gut 1978;19(9):779-782. Liu C, Wang J, Yang J. Hawrelak, J. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. View abstract. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. View abstract. Zhong Xi Yi Jie He Za Zhi 1991;11(3):150-2, 133. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Hum Exp Toxicol 2012;31(12):1295-1298. Arch.Pharm Res 2012;35(11):1945-1952. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. 2020;2020:8401239. J Ethnopharmacol. BMJ 1997;314:731-2. Am.J Chin Med 2004;32(4):569-578. Sato H, Goto W, Yamamura J, et al. Liang, R., Chen, M. R., and Xu, X. View abstract. J Intern Med 1999;245:307-10. They also have a range of other intriguing activities. Phytother Res 2006;20(8):687-695. Gut 1973;14(9):711-715. J Endocrinol Invest 1990;13(10):847-848. View abstract. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy 2000;20(1):38-41. View abstract. [The nature of an anticoagulant isolated from peonies in the central zone of Russia]. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. This might decrease the effects of midazolam. Vestn.Dermatol.Venerol. View abstract. Ann Pharmacother 2003;37(6):836-838. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Monograph. Be sure to have your blood checked regularly. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. Sontia B, Mooney J, Gaudet L, Touyz RM. World J Gastroenterol 2005;11:2124-9. . Black licorice contains a compound that comes from licorice root that can lower your potassium levels. View abstract. View abstract. View abstract. Xu Y, Li X, Chen T, et al. Man SC, Li XB, Wang HH, et al. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Some possible side effects with oral use include rash, itching, nasal symptoms, or stomach discomfort, but these are uncommon. Armanini, D., Castello, R., Scaroni, C., Bonanni, G., Faccini, G., Pellati, D., Bertoldo, A., Fiore, C., and Moghetti, P. Treatment of polycystic ovary syndrome with spironolactone plus licorice. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Int Immunopharmacol 2012;14(1):27-31. View abstract. Li G, Simmler C, Chen L, et al. View abstract. Taking licorice along with "water pills" might make potassium levels drop too low. J Cardiovasc.Surg (Torino) 2000;41(4):631-632. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. View abstract. View abstract. View abstract. [Treatment of chronic hepatitis B. Kwon S, Jin C, Cho SY, et al. Ann Noninvasive Electrocardiol. Lapi F, Gallo E, Bernasconi S, et al. Planta Med 2003;69(12):1113-1118. J Assoc Physicians India 1989;37(10):647. View abstract. J Endocrinol Invest 1996;19:624-9. Psychoneuroendocrinology. J Hum Hypertens 2003;17(2):125-131. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. A pilot study. White peony ( bai shao in Chinese) is root without any bark, while red peony . View abstract. View abstract. Fugh-Berman, A. Herb-drug interactions. Engqvist, A., von Feilitzen, F., Pyk, E., and Reichard, H. Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer. View abstract. View abstract. Tsuda T, Sugaya A, Ohguchi H, et al. View abstract. Badr, A. E., Omar, N., and Badria, F. A. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. View abstract. A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating microbiota and reducing inflammation . Cai Y, Yuan Q, Xu K, et al. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. Astragalus may be safe when used orally and appropriately. View abstract. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. View abstract. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. Ital J Neurol Sci 1983;4(4):493-497. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. View abstract. Lancet 1990;335(8697):1060-3. J Am Coll.Nutr 2007;26(3):209-218. View abstract. Hyodo T, Taira T, Kumakura M, et al. Klin Wochenschr 1983;61:303-5. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. Antiviral Res 12-11-1988;10(6):289-298. Phytomedicine 2003;10:271-85. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. View abstract. Arch Pharm Res 2003;26(10):832-839. Balakrishnan, V., Pillai, M. V., Raveendran, P. M., and Nair, C. S. Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer. 2005 - 2023 WebMD LLC. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. View abstract. ""- . Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. Some sources claim that it's contraindicated during pregnancy . J Agric Food Chem 6-13-2007;55(12):4691-4697. Holtmann G, Madisch A, Juergen H, et al. It's not suggested to take St. John's wort if you take blood thinners. View abstract. Overview. Biol Pharm Bull. J Altern Complement Med 2009;15(4):439-443. Phytother Res 1988;2(3):140-145. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. Eur.Arch.Paediatr.Dent 2010;11(6):274-278. Am J Chin Med 2003;31:445-53. . View abstract. Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Hypertension encephalopathy after liquorice ingestion. Abe K, Higurashi T, Takahashi M, et al. But not everyone will have the side . Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. [Application of dannang recipe no. 2008;9(3):88-98. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Paeonia lactiflora : Peony is another popular anti-androgenic herb. View abstract. View abstract. J Altern Complement Med. N Engl J Med 1990;322:849-50. View abstract. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. Br J Clin Pharmacol 2008;66:572-4. Fitoterapia 2006;77(7-8):613-614. View abstract. 2007;30(7):1271-7. Thom E and Wollan T. A controlled clinical study of kanjang mixture in the treatment of uncomplicated upper respiratory tract infections. Digestion 2004;69:45-52. View abstract. Large amounts of licorice can decrease potassium levels in the body. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. View abstract. Licorice might decrease how well cisplatin works. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Nishioka, K. and Seguchi, T. Contact allergy due to oil-soluble licorice extracts in cosmetic products. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Braz J Infect Dis 2016;20(6):534-8. Amato P, Christophe S, Mellon PL. Bannister, B., Ginsburg, R., and Shneerson, J. Cardiac arrest due to liquoriceinduced hypokalaemia. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. The dogs treated with the herbal mixture saw a 37.5 percent improvement . This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. View abstract. J Steroid Biochem Mol Biol 1994;49:81-5. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Saw palmetto. 2010 Nov;35(10):1587-93. A double-blind, randomized, placebo-controlled, multicenter trial. Practitioners still sometimes suggest whole licorice for cough . A., Lee, S. H., and Lee, S. M. Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice. J Clin Endocrinol Metab 2003;88:2384-92. View abstract. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. View abstract. Zhonghua Yi Xue Za Zhi 1983;63:477-81. Am J Chin Med 1992;20(3-4):313-317. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. View abstract. Licorice can decrease how quickly the body breaks down corticosteroids. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Ned.Tijdschr Geneeskd. J Endocrinol Invest 2003;26:646-50. Zhang W, Dai SM. All rights reserved. J Altern Complement Med 2000;6:557-9. Nephron 2002;90:240. Practitioner 1973;210:820-3. Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. Lancet 2-10-1979;1(8111):319. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. A., Motallebnejad, M., and Khanian, M. The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Mouthwash Containing Glycyrrhiza uralensis Extract for Preventing Dental Caries. Cancer Lett 12-10-2001;174(1):17-24. But the potential side effects are real enough. J Dermatolog Treat 2003;14(3):153-157. WebMD does not provide medical advice, diagnosis or treatment. Pharm Biol. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Common side effects of licorice include: Absence of a menstrual period . Chinese herbal medicine for atopic eczema. View abstract. 2017 Sep;31(9):1330-1340. For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Medicine (Baltimore) 2019;98(35):e16601. Oral Dis 2012;18(1):32-39. 1991;78(1-2):1-6. View abstract. Kim YR, Nam SH. J Pharmacol Exp Ther 2006;316:1369-77. [A plant extract and its modified preparation in functional dyspepsia. View abstract. Most clinical trials have found that when Peony is combined with Licorice Rt. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. Horm.Res 1999;52(5):253-255. Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. Bai, Y. S., Zhou, C. Y., and Wang, J. Q. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. View abstract. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. View abstract. Turpie AG, Runcie J, Thomson TJ. The effect of Glycyrrhiza glabra L. on primary dysmenorrhea compared with ibuprofen: A randomized, triple-blind controlled trial. View abstract. The chemicals in licorice are thought to . View abstract. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. The effects of licorice containing diphenhydramine solution on recurrent aphthous stomatitis: A double-blind, randomized clinical trial. View abstract. QJM 2011;104(12):1093-1095. View abstract. J Gastroenterol 1996;31(5):691-695. Fitoterapia 2004;75:45-9.. View abstract. 2014 Jun;23(3):189-92. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. Asia Pac.J Clin Nutr 2008;17(1):17-22. Luo, Y. G., Liu, Y. Q., and Hu, J. Complement Ther Clin Pract. Kang, J. H., Park, Y. H., Choi, S. W., Yang, E. K., and Lee, W. J. Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. View abstract. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . 2001;21(7):501-503. View abstract. View abstract. A., Keller, W. J., Pereira, M. A., and Kinghorn, A. D. Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). Licorice that has had this substance removed (called DGL for deglycyrrhizinated licorice) may not have the same degree of side effects. We could use compounds in these foods to . Am J Chin Med 2001;29(3-4):459-467. Removes excess melanin: Licorice extract brightens the skin in another way, too. Cancer 1997;79(8):1494-1500. J Tradit.Chin Med 2010;30(1):47-50. This versatile anti-inflammatory plant can benefit digestive issues, hormone health, and skin health as well as helping ease problems with menstruation and menopause. J Peripher.Nerv.Syst. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. Brit Med J 1952;1:360-361. 6 Top Celery Juice Benefits & Side Effects. View abstract. [13] A study in Japan compared the use of a . Plant Description. Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. This can increase the effects and side effects of corticosteroids. Additional reporting by Meghan De Maria. No side effects or changes in liver function tests occurred during the study. Rev Med Brux 2008;29(5):490-493. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. White Peony is technically named Peonia lactiflora, and in Chinese, it is named Bai Shao. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. West J Med 1997;167(3):184-185. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. Amaryan G, Astvatsatryan V, Gabrielyan E, et al. View abstract. October 15, 2021. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . View abstract. Here are a few of them: . 2020 Dec;58(1):352-356. View abstract. View abstract. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. N Engl J Med 1990;322:850. View abstract. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. View abstract. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. 2003;23(8):593-595. Altern Med Rev 1999;4(3):178-188. View abstract. Licorice has been used as a medicinal plant from 2.500 years. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Russo S, Mastropasqua M, Mosetti MA, et al. 2000;20(3):173-175. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. View abstract. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. Phytother Res 2012;26(9):1381-1384. Nephrologie 1993;14(4):177-181. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. View abstract. Lancet 2000;355(9198):134-138. View abstract. View abstract. Phytother Res. View abstract. View abstract. J Gastroenterol Hepatol 1999;14(11):1093-1099. View abstract. View abstract. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Yang HO, Ko WK, Kim JY, Ro HS. View abstract. The sweet cake that reaches parts other cakes can't! Unfortunately, there is not much scientific evidence around the use of Licorice in Hirsutism, and more studies are needed to prove if it's effective in hirsutism or not. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. View abstract. Kraus SD, Kaminskis A. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. Complement Ther Med. J Altern Complement Med 2010;16(10):1065-1071. Ito A, Hayashi N, Katayama K, and et al. N Engl J Med. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress.